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KMID : 0980720110300010029
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Keimyung Medical Journal
2011 Volume.30 No. 1 p.29 ~ p.42
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The Effect of Intravitreal Triamcinolone Acetonide or Avastin Injection According to the OCT Patterns of Macular Edema
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Jang Ji-Hye
Kim Yu-Cheol
Kim Kwang-Soo
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Abstract
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This study was aimed to compare clinical outcomes according to the morphologic patterns of macular edema after a single intravitreal injection of triamcinolone acetonide (TA) or avastin for the treatment of macular edema. One hundred and thirty-eight eyes with diabetic macular edema (DME) or macular edema in branch retinal vein occlusion (BVOME) were enrolled in this study. Macular edema was classified into four morphologic patterns based on optical coherence tomography (OCT): Cystoid macular edema, sponge-like macular edema, serous macular detachment, and combined macular edema. Visual acuity and central macular thickness (CMT) were compared between the groups at 2 weeks, 1, 2 and 6 months after therapy. The combined macular edema type in DME and BVOME patients showed better improvement of visual acuity and foveal thickness. In aspect of the treatment for macular edema, the sponge-like macular edema
treated intravitreal TA injection revealed worst improvement of visual acuity. The significant reductions of CMT were observed all types of macular edema after the procedure. There was no significant difference about a recurrence of macular edema between the groups. This study revealed that the pattern of macular edema using OCT will help to determine the anatomic and functional effect of intravitreal injection.
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KEYWORD
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Intravitreal avastine injection, Intravitreal triamcinolone acetonide injection, Macular edema type
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